Select Publications Involving Eve Technologies™ Assay Services

Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology, T Cells

GP96 is a GARP chaperone and controls regulatory T cell functions.
Zhang Y, Wu BX, Metelli A, Thaxton JE, Hong F, Rachidi S, Ansa-Addo E, Sun S, Vasu C, Yang Y, Liu B, Li Z.
J Clin Invest. 2015 Jan 20. pii: 79014. doi: 10.1172/JCI79014. [Epub ahead of print]


Assay Services Used: Human Cytokine Array, Custom 17-plex
Disease / Biomarker Category: Virology, Immunology, Vaccine, Influenza

Effect of Immunosuppression on Th4 and B-cell Responses to Influenza Vaccination.
Egli A1, Humar A2, Widmer LA3, Lisboa LF4, Santer DM4, Mueller T5, Stelling J3, Baluch A6, O’Shea D4, Houghton M4, Kumar D2.
J Infect Dis. 2015 Jan 14. pii: jiv015. [Epub ahead of print]


Assay Services Used: Human MMP & TIMP Discovery assay
Assay Services Used: Human Cytokine Array Discovery Assay, 64 Biomarker Multiplex
Disease / Biomarker Category: Cancer

Tumour cell-derived extracellular vesicles interact with mesenchymal stem cells to modulate the microenvironment and enhance cholangiocarcinoma growth.
Haga H11, Yan IK1, Takahashi K1, Wood J1, Zubair A2, Patel T3.
J Extracell Vesicles. 2015 Jan 2;4:24900. doi: 10.3402/jev.v4.24900. eCollection 2015.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology, T Cells, Pathogen, Parasite

Splenic B Cells from Hymenolepis diminuta Infected Mice Ameliorate ColitisIndependent of T Cells and via Cooperation with Macrophages.
Reyes JL1, Wang A1, Fernando MR1, Graepel R1, Leung G1, van Rooijen N2, Sigvardsson M3, McKay DM4.
J Immunol. 2015 Jan 1;194(1):364-78. doi: 10.4049/jimmunol.1400738. Epub 2014 Dec 1.


Assay Services Used: Human Cytokine Array Discovery Assay, 64 Biomarker Multiplex
Disease / Biomarker Category: Virology, Immunology, HIV

Medroxyprogesterone acetate regulates HIV-1 uptake and transcytosis, but not replication, in primary genital epithelial cells, resulting in enhanced T-cell infection.
Ferreira VH1, Dizzell S1, Nazli A1, Kafka JK1, Mueller K1, Nguyen P1, Tremblay MJ2, Cochrane A3, Kaushic C1.
J Infect Dis. 2014 Dec 23. pii: jiu832. [Epub ahead of print]


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Assay Services Used: Human Cytokine Array, Custom 17-plex
Disease / Biomarker Category: Virology, Immunology, Vaccine

IL-28B is a Key Regulator of B- and T-Cell Vaccine Responses against Influenza.
Egli A, Santer DM, O’Shea D, Barakat K, Syedbasha M, Vollmer M, Baluch A, Bhat R, Groenendyk J, Joyce MA, Lisboa LF, Thomas BS, Battegay M, Khanna N, Mueller T, Tyrrell DL, Houghton M, Humar A, Kumar D.
PLoS Pathog. 2014 Dec 11;10(12):e1004556. doi: 10.1371/journal.ppat.1004556.


Assay Services Used: Porcine Cytokine Array, 13-plex Discovery Assay
Disease / Biomarker Category: Pregnancy, Immunology

mRNA Destabilizing Factors: Tristetraprolin Expression at the Porcine Maternal-Fetal Interface.
Khalaj K1, Wessels JM, Kridli RT, Bidarimath M, LaMarre J, Tayade C.
Am J Reprod Immunol. 2014 Dec 11. doi: 10.1111/aji.12347. [Epub ahead of print]


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Inflammation

Positive allosteric modulation of the adenosine A2a receptor attenuates inflammation.
Welihinda AA, Amento EP.
J Inflamm (Lond). 2014 Nov 28;11(1):37. doi: 10.1186/s12950-014-0037-0. eCollection 2014.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Assay Services Used: TGF-beta 3-plex Discovery Assay
Disease / Biomarker Category: Stem Cells

MSCs Conditioned Media and Umbilical Cord Blood Plasma Metabolomics and Composition.
Pereira T, Ivanova G, Caseiro AR, Barbosa P, Bártolo PJ, Santos JD, Luís AL, Maurício AC.
PLoS One. 2014 Nov 25;9(11):e113769.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology, T Cells, Sepsis

T helper type 2-polarized invariant natural killer T cells reduce disease severity in acute intra-abdominal sepsis.
Anantha RV1, Mazzuca DM, Xu SX, Porcelli SA, Fraser DD, Martin CM, Welch I, Mele T, Haeryfar SM, McCormick JK.
Clin Exp Immunol. 2014 Nov;178(2):292-309. doi: 10.1111/cei.12404.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology, Respiratory System

Abrogation of Airway Hyperresponsiveness but not Inflammation by Rho kinase Insufficiency.
Kasahara DI1, Ninin FM, Wurmbrand AP, Liao JK, Shore SA.
Clin Exp Allergy. 2014 Oct 16. doi: 10.1111/cea.12438. [Epub ahead of print]


Assay Services Used: Human Immunoglobulin Isotyping, Custom 6-plex
Disease / Biomarker Category: Eosinophilic Esophagitis, Immunology

Eosinophilic esophagitis in adults is associated with IgG4 and not mediated by IgE.
Clayton F1, Fang JC2, Gleich GJ3, Lucendo AJ4, Olalla JM5, Vinson LA2, Lowichik A6, Chen X7, Emerson L7, Cox K2, O’Gorman MA8, Peterson KA2.
Gastroenterology. 2014 Sep;147(3):602-9. doi: 10.1053/j.gastro.2014.05.036. Epub 2014 Jun 4.


Assay Services Used: Human Cytokine Array Discovery Assay, 64 Biomarker Multiplex
Disease / Biomarker Category: Virology, Immunology

Induction of IL-17A Precedes Development of Airway Hyperresponsiveness during Diet-Induced Obesity and Correlates with Complement Factor D.
Mathews JA1, Wurmbrand AP1, Ribeiro L1, Neto FL1, Shore SA1.
Front Immunol. 2014 Sep 15;5:440. doi: 10.3389/fimmu.2014.00440. eCollection 2014.


Assay Services Used: Human CD8+ T Cell Custom 6-plex
Disease / Biomarker Category: Immunology, T Cells, Tuberculosis

Cytokine response to selected MTB antigens in Ghanaian TB patients, before and at 2 weeks of anti-TB therapy is characterized by high expression of IFN-? and Granzyme B and inter- individual variation.
Mensah GI1, Addo KK, Tetteh JA, Sowah S, Loescher T, Geldmacher C, Jackson-Sillah D.
BMC Infect Dis. 2014 Sep 10;14:495. doi: 10.1186/1471-2334-14-495.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Dentistry, Inflammation, Bacterial Pathogens

Synergistic anti-inflammatory activity of the antimicrobial peptides human beta-defensin-3 (hBD-3) and cathelicidin (LL-37) in a three-dimensional co-culture model of gingival epithelial cells and fibroblasts.
Bedran TB1, Mayer MP2, Spolidorio DP3, Grenier D4.
PLoS One. 2014 Sep 4;9(9):e106766. doi: 10.1371/journal.pone.0106766. eCollection 2014.


Assay Services Used: Human MMP & TIMP Discovery Assay
Disease / Biomarker Category: Cancer

CIP4 promotes lung adenocarcinoma metastasis and is associated with poor prognosis.
Truesdell P1, Ahn J1, Chander H1, Meens J1, Watt K1, Yang X2, Craig AW1.
Oncogene. 2014 Sep 1. doi: 10.1038/onc.2014.280. [Epub ahead of print]


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology, Sepsis, Toxic Shock

Superantigens subvert the neutrophil response to promote abscess formation andenhance Staphylococcus aureus survival in vivo.
Xu SX1, Gilmore KJ2, Szabo PA1, Zeppa JJ1, Baroja ML3, Haeryfar SM4, McCormick JK5.
Infect Immun. 2014 Sep;82(9):3588-98. doi: 10.1128/IAI.02110-14. Epub 2014 Jun 9.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Arthritis, Inflammation

A computational method to differentiate normal individuals, osteoarthritis and rheumatoid arthritis patients using serum biomarkers.
Heard BJ, Rosvold JM, Fritzler MJ, El-Gabalawy H, Wiley JP, Krawetz RJ.
J R Soc Interface. 2014 Aug 6;11(97):20140428. doi: 10.1098/rsif.2014.0428.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Cancer, Radiation, Skin, Immunology

Vasculotide, an Angiopoietin-1 mimetic, reduces acute skin ionizing radiation damage in a preclinical mouse model.
Korpela E, Yohan D, Chin LC, Kim A, Huang X, Sade S, Van Slyke P, Dumont DJ, Liu SK1.
BMC Cancer. 2014 Aug 26;14:614. doi: 10.1186/1471-2407-14-614.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology

An in vitro model of innate lymphoid cell function and differentiation.
Allan DS1, Kirkham CL1, Aguilar OA1, Qu LC1, Chen P1, Fine JH1, Serra P1, Awong G1, Gommerman JL2, Zúñiga-Pflücker JC1, Carlyle JR1.
Mucosal Immunol. 2014 Aug 20. doi: 10.1038/mi.2014.71. [Epub ahead of print]


Assay Services Used: Human Cytokine Array Discovery Assay, 64 Biomarker Multiplex
Assay Services Used: Human MMP & TIMP Discovery Assay
Disease / Biomarker Category: Cancer, Radiation, Skin, Immunology

Serum with phospholipase A2 receptor autoantibodies interferes with podocyteadhesion to collagen.
Škoberne A1, Behnert A, Teng B, Fritzler MJ, Schiffer L, Pajek J, Lindič J, Haller H, Schiffer M.
Eur J Clin Invest. 2014 Aug;44(8):753-65. doi: 10.1111/eci.12292.


Assay Services Used: Human Cytokine Array Discovery Assay
Disease / Biomarker Category: Cancer, Inflammation, Liver

Identification of prognostic inflammatory factors in colorectal liver metastases.
Hamilton TD, Leugner D, Kopciuk K, Dixon E, Sutherland FR, Bathe OF1.
BMC Cancer. 2014 Jul 28;14:542. doi: 10.1186/1471-2407-14-542.


Assay Services Used: Rat Cytokine Array Discovery Assay, 27 Biomarker Multiplex
Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Immunology, Parasite, Pathogen

Gal-lectin-dependent contact activates the inflammasome by invasive Entamoebahistolytica.
Mortimer L1, Moreau F1, Cornick S1, Chadee K1.
Mucosal Immunol. 2014 Jul;7(4):829-41. doi: 10.1038/mi.2013.100. Epub 2013 Nov 20.


Assay Services Used: Human Cytokine Array Discovery Assay, 64 Biomarker Multiplex
Disease / Biomarker Category: Cancer

Reduced ING1 levels in breast cancer promotes metastasis.
Thakur S, Singla AK, Chen J, Tran U, Yang Y, Salazar C, Magliocco A, Klimowicz A, Jirik F, Riabowol K.
Oncotarget. 2014 Jun 30;5(12):4244-56.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Immunology, Cancer

DMXAA causes tumor site-specific vascular disruption in murine non-small cell lung cancer, and like the endogenous non-canonical cyclicdinucleotide STING agonist, 2’3′-cGAMP, induces M2 macrophagerepolarization.
Downey CM1, Aghaei M1, Schwendener RA2, Jirik FR1.
PLoS One. 2014 Jun 18;9(6):e99988. doi: 10.1371/journal.pone.0099988. eCollection 2014.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Virology, Immunology, Ankylosing Spondylitis

HLA-B27, but not HLA-B7, immunodominance to influenza is ERAP dependent.
Akram A1, Lin A2, Gracey E1, Streutker CJ3, Inman RD4.
J Immunol. 2014 Jun 15;192(12):5520-8. doi: 10.4049/jimmunol.1400343. Epub 2014 May 16.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Metabolism, Immunology

Macrophage depletion disrupts immune balance and energy homeostasis.
Lee B1, Qiao L1, Kinney B1, Feng GS2, Shao J1.
PLoS One. 2014 Jun 9;9(6):e99575. doi: 10.1371/journal.pone.0099575. eCollection 2014.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Multiple Sclerosis, Neurodegeneration, Immunology

Laquinimod reduces neuroaxonal injury through inhibiting microglial activation.
Mishra MK1, Wang J1, Keough MB1, Fan Y1, Silva C1, Sloka S2, Hayardeny L3, Brück W4, Yong VW1.
Ann Clin Transl Neurol. 2014 Jun;1(6):409-22. doi: 10.1002/acn3.67. Epub 2014 May 26.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Pathogen, Sepsis

Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC Class II-dependent manner.
Kasper KJ1, Zeppa JJ1, Wakabayashi AT1, Xu SX1, Mazzuca DM1, Welch I2, Baroja ML3, Kotb M4, Cairns E5, Cleary PP6, Haeryfar SM3, McCormick JK3.
PLoS Pathog. 2014 May 29;10(5):e1004155. doi: 10.1371/journal.ppat.1004155. eCollection 2014.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Metabolism, Immunology

C/EBPα regulates macrophage activation and systemic metabolism.
Lee B, Qiao L, Lu M, Yoo HS, Cheung W, Mak R, Schaack J, Feng GS, Chi NW, Olefsky JM, Shao J.
Am J Physiol Endocrinol Metab. 2014 May 15;306(10):E1144-54. doi: 10.1152/ajpendo.00002.2014. Epub 2014 Apr 1.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Respiratory System, Environment, Inflammation

γδ T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFα.
Mathews JA, Williams AS, Brand JD, Wurmbrand AP, Chen L, Ninin FM, Si H, Kasahara DI, Shore SA.
PLoS One. 2014 May 13;9(5):e97707. doi: 10.1371/journal.pone.0097707. eCollection 2014.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology, T Cells, Dermatology, Skin, Vitiligo

A quantitative increase in regulatory T cells controls development of vitiligo.
Chatterjee S1, Eby JM2, Al-Khami AA1, Soloshchenko M1, Kang HK2, Kaur N1, Naga OS1, Murali A1, Nishimura MI3, Le Poole IC2, Mehrotra S1.
J Invest Dermatol. 2014 May;134(5):1285-94. doi: 10.1038/jid.2013.540. Epub 2013 Dec 23.


Assay Services Used: Human Cytokine Array Th17 Panel, 6 Biomarker Multiplex
Disease / Biomarker Category: IBD, Crohn’s, Inflammation

Opposing effects of smoking in ulcerative colitis and Crohn’s disease may be explained by differential effects on dendritic cells.
Ueno A1, Jijon H, Traves S, Chan R, Ford K, Beck PL, Iacucci M, Fort Gasia M, Barkema HW, Panaccione R, Kaplan GG,Proud D, Ghosh S.
Inflamm Bowel Dis. 2014 May;20(5):800-10. doi: 10.1097/MIB.0000000000000018.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology, Sepsis

A robust scoring system to evaluate sepsis severity in an animal model.
Shrum B, Anantha RV, Xu SX, Donnelly M, Haeryfar SM, McCormick JK, Mele T1.
BMC Res Notes. 2014 Apr 12;7:233. doi: 10.1186/1756-0500-7-233.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology, Autoimmune, Lupus

Phospholipid binding proteins differ in their capacity to induce autoantibodies and murine systemic lupus erythematosus.
Levine J1, Subang R2, Setty S3, Cabrera J4, Laplante P2, Fritzler M5, Rauch J6.
Lupus. 2014 Apr 2;23(8):752-768. [Epub ahead of print]


Assay Services Used: Human Cytokine Array Discovery Assay
Disease / Biomarker Category: Cancer, Inflammation

Immune chaperone gp96 drives the contributions of macrophages to inflammatory colon tumorigenesis.
Morales C, Rachidi S, Hong F, Sun S, Ouyang X, Wallace C, Zhang Y, Garret-Mayer E, Wu J, Liu B, Li Z.
Cancer Res. 2014 Jan 15;74(2):446-59. doi: 10.1158/0008-5472.CAN-13-1677.


Assay Services Used: Rat Cytokine Array Discovery Assay, 27 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Optometry

ROS detoxification and proinflammatory cytokines are linked by p38 MAPK signaling in a model of mature astrocyte activation.
Nahirnyj A1, Livne-Bar I1, Guo X1, Sivak JM2.
PLoS One. 2013 Dec 23;8(12):e83049. doi: 10.1371/journal.pone.0083049. eCollection 2013.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Diabetes

Long-term hemodynamic and molecular effects persist after discontinued renin-angiotensin system blockade in patients with type 1 diabetes mellitus.
Cherney DZ1, Zinman B, Kennedy CR, Moineddin R, Lai V, Yang S, Miller JA, Prokopec SD, Boutros PC,Scholey JW, Reich HN.
Kidney Int. 2013 Dec;84(6):1246-53. doi: 10.1038/ki.2013.221. Epub 2013 Jun 12.


Assay Services Used: Rat Gut Hormone Custom Array Assay – 8 Biomarker Multiplex
Disease / Biomarker Category: Diet, Nutrition, Gut Hormones

A maternal high-protein diet predisposes female offspring to increased fat mass in adulthood whereas a prebiotic fibre diet decreases fat mass in rats.
Hallam MC, Reimer RA.
2. Br J Nutr. 2013 Nov;110(9):1732-41. doi: 10.1017/S0007114513000998. Epub 2013 Apr 8.
Authors did not specify Eve Tech generated data.


Assay Services Used: Human Cytokine Array Th17 Panel, 6 Biomarker Multiplex
Disease / Biomarker Category: IBD, Crohn’s, Inflammation

Increased prevalence of circulating novel IL 17 secreting Foxp3 expressing CD4+ Tcells and defective suppressive function of circulating Foxp3+ regulatory cells support plasticity between Th17 and regulatory T cells in inflammatory bowel disease patients.
Ueno A1, Jijon H, Chan R, Ford K, Hirota C, Kaplan GG, Beck PL, Iacucci M, Fort Gasia M, Barkema HW, Panaccione R, Ghosh S.
Inflamm Bowel Dis. 2013 Nov;19(12):2522-34. doi: 10.1097/MIB.0b013e3182a85709.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Diabetes, Immunology

The effect of aliskiren on urinary cytokine/chemokine responses to clamped hyperglycaemia in type 1 diabetes.
Cherney DZ1, Reich HN, Scholey JW, Daneman D, Mahmud FH, Har RL, Sochett EB.
Diabetologia. 2013 Oct;56(10):2308-17. doi: 10.1007/s00125-013-3000-3. Epub 2013 Jul 28.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Arthritis, Inflammation

Monocyte chemotactic protein-1 inhibits chondrogenesis of synovial mesenchymal progenitor cells: an in vitro study.
Harris Q1, Seto J, O’Brien K, Lee PS, Kondo C, Heard BJ, Hart DA, Krawetz RJ.
Stem Cells. 2013 Oct;31(10):2253-65. doi: 10.1002/stem.1477.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Alzheimer’s, Neurology, Inflammation, Air Pollution, Prion Protein

Brain immune interactions and air pollution: macrophage inhibitory factor (MIF), prion cellular protein (PrP(C)), Interleukin-6 (IL-6), interleukin 1 receptor antagonist (IL-1Ra), and interleukin-2 (IL-2) in cerebrospinal fluid and MIF in serum differentiate urban children exposed to severe vs. low air pollution.
Calderón-Garcidueñas L, Cross JV, Franco-Lira M, Aragón-Flores M, Kavanaugh M, Torres-Jardón R, Chao CK, Thompson C, Chang J, Zhu H, D’Angiulli A.
Front Neurosci. 2013 Oct 10;7:183. doi: 10.3389/fnins.2013.00183. eCollection 2013.


Assay Services Used: Rat Gut Hormone Custom Array Assay – 8 Biomarker Multiplex
Disease / Biomarker Category: Diet, Nutrition, Gut Hormones

Combined effects of oligofructose and Bifidobacterium animalis on gut microbiota and glycemia in obese rats.
Bomhof MR, Saha DC, Reid DT, Paul HA, Reimer RA.
1. Obesity (Silver Spring). 2013 Oct 1. doi: 10.1002/oby.20632. [Epub ahead of print]
Authors did not specify Eve Tech generated data.t


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Metabolism, Diabetes, Cardiology

Short term exercise induces PGC 1α, ameliorates inflammation andincreases mitochondrial membrane proteins but fails to increaserespiratory enzymes in aging diabetic hearts.
Botta A1, Laher I, Beam J, Decoffe D, Brown K, Halder S, Devlin A, Gibson DL, Ghosh S.
PLoS One. 2013 Aug 1;8(8):e70248. doi: 10.1371/journal.pone.0070248. Print 2013.


Assay Services Used: Human Cytokine Array Custom Assay, 6 Biomarker Multiplex
Assay Services Used: TGF-beta 1 Assay
Disease / Biomarker Category: Diabetes, Inflammation

Clinical value of inflammatory urinary biomarkers in overt diabetic nephropathy: aprospective study.
Verhave JC1, Bouchard J, Goupil R, Pichette V, Brachemi S, Madore F, Troyanov S.
Diabetes Res Clin Pract. 2013 Sep;101(3):333-40. doi: 10.1016/j.diabres.2013.07.006. Epub 2013 Jul 20.


Assay Services Used: Human Cytokine Array Custom Assay, 35 Biomarker Multiplex
Disease / Biomarker Category: Obesity, Respiratory System, Inflammation

Obesity and airway responsiveness: role of TNFR2.
Williams AS1, Chen L, Kasahara DI, Si H, Wurmbrand AP, Shore SA.
Pulm Pharmacol Ther. 2013 Aug;26(4):444-54. doi: 10.1016/j.pupt.2012.05.001. Epub 2012 May 11.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Alzheimer’s, Parkinson’s, Neurology, Inflammation, Air Pollution

Flavonol-rich dark cocoa significantly decreases plasma endothelin-1 and improves cognition in urban children.
Calderón-Garcidueñas L, Mora-Tiscareño A, Franco-Lira M, Cross JV, Engle R, Aragón-Flores M, Gómez-Garza G, Jewells V, Medina-Cortina H, Solorio E, Chao CK, Zhu H, Mukherjee PS, Ferreira-Azevedo L, Torres-Jardón R, D’Angiulli A.
Front Pharmacol. 2013 Aug 22;4:104. doi: 10.3389/fphar.2013.00104. eCollection 2013.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Arthritis, Inflammation

Intraarticular and systemic inflammatory profiles may identify patients with osteoarthritis.
Heard BJ1, Fritzler MJ, Wiley JP, McAllister J, Martin L, El-Gabalawy H, Hart DA, Frank CB, Krawetz R.
J Rheumatol. 2013 Aug;40(8):1379-87. doi: 10.3899/jrheum.121204. Epub 2013 May 15.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Respiratory System

Effects of copy center particles on the lungs: a toxicological characterization using a Balb/c mouse model.
Pirela S1, Molina R, Watson C, Cohen JM, Bello D, Demokritou P, Brain J.
Inhal Toxicol. 2013 Aug;25(9):498-508. doi: 10.3109/08958378.2013.806614. Epub 2013 Jul 29.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology

Cannabinoid 1 receptors are critical for the innate immune response to TLR4stimulation.
Duncan M1, Galic MA, Wang A, Chambers AP, McCafferty DM, McKay DM, Sharkey KA, Pittman QJ.
Am J Physiol Regul Integr Comp Physiol. 2013 Aug 1;305(3):R224-31. doi: 10.1152/ajpregu.00104.2013. Epub 2013 Jun 5.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Inflammation

Selective suppression of endothelial cytokine production by progesterone receptor.
Goddard LM1, Ton AN, Org T, Mikkola HK, Iruela-Arispe ML.
Vascul Pharmacol. 2013 Jul-Aug;59(1-2):36-43. doi: 10.1016/j.vph.2013.06.001.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Fungal Pathogen, Immunity

Cryptococcus gattii is killed by dendritic cells, but evades adaptive immunity by failing to induce dendritic cell maturation.
Huston SM, Li SS, Stack D, Timm-McCann M, Jones GJ, Islam A, Berenger BM, Xiang RF, Colarusso P, Mody CH.
J Immunol. 2013 Jul 1;191(1):249-61. doi: 10.4049/jimmunol.1202707. Epub 2013 Jun 5.


Assay Services Used: Human Cytokine Array Discovery Assay, 64 Biomarker Multiplex
Disease / Biomarker Category: Virology, Immunology

The lack of maturation of Ebola virus-infected dendritic cells results from the cooperative effect of at least two viral domains.
Lubaki NM1, Ilinykh P, Pietzsch C, Tigabu B, Freiberg AN, Koup RA, Bukreyev A.
J Virol. 2013 Jul;87(13):7471-85. doi: 10.1128/JVI.03316-12. Epub 2013 Apr 24.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Toxicity

Role of the adiponectin binding protein, T cadherin (cdh13),in pulmonary responses to subacute ozone.
Kasahara DI1, Williams AS, Benedito LA, Ranscht B, Kobzik L, Hug C, Shore SA.
PLoS One. 2013 Jun 6;8(6):e65829. doi: 10.1371/journal.pone.0065829. Print 2013.


Assay Services Used: Human Cytokine Array Custom Assay, 20 Biomarker Multiplex
Disease / Biomarker Category: Immunology, Autoimmune

B cell depletion with rituximab in patients with primary biliary cirrhosis refractory toursodeoxycholic acid.
Myers RP1, Swain MG, Lee SS, Shaheen AA, Burak KW.
Am J Gastroenterol. 2013 Jun;108(6):933-41. doi: 10.1038/ajg.2013.51. Epub 2013 May 7.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Diabetes, Inflammation

The effect of renal hyperfiltration on urinary inflammatory cytokines/chemokines in patients with uncomplicated type 1 diabetes mellitus.
Har R, Scholey JW, Daneman D, Mahmud FH, Dekker R, Lai V, Elia Y, Fritzler ML, Sochett EB, Reich HN, Cherney DZ.
Diabetologia. 2013 May;56(5):1166-73. doi: 10.1007/s00125-013-2857-5. Epub 2013 Feb 15.


Assay Services Used: Custom Biomarker
Disease / Biomarker Category: Cancer

CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancer.
Xu J1, Escamilla J, Mok S, David J, Priceman S, West B, Bollag G, McBride W, Wu L.
Cancer Res. 2013 May 1;73(9):2782-94. doi: 10.1158/0008-5472.CAN-12-3981. Epub 2013 Feb 15.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Colitis, Inflammation

TRPM8 activation attenuates inflammatory responses in mouse models of colitis.
Ramachandran R1, Hyun E, Zhao L, Lapointe TK, Chapman K, Hirota CL, Ghosh S, McKemy DD, Vergnolle N, Beck PL,Altier C, Hollenberg MD.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7476-81. doi: 10.1073/pnas.1217431110. Epub 2013 Apr 17.


Assay Services Used: Custom Peptide Array
Disease / Biomarker Category: Autoimmune

An anti phospholipase A2 receptor quantitative immunoassay and epitope analysis in membranous nephropathy reveals different antigenic domains of the receptor.
Behnert A1, Fritzler MJ, Teng B, Zhang M, Bollig F, Haller H, Skoberne A, Mahler M, Schiffer M.
PLoS One. 2013 Apr 29;8(4):e61669. doi: 10.1371/journal.pone.0061669. Print 2013.


Assay Services Used: Human Apoptosis Array 3-Plex
Disease / Biomarker Category: Apoptosis, Cardiology

Transplantation of autologously derived mitochondria protects the heartfrom ischemia-reperfusion injury.
Masuzawa A1, Black KM, Pacak CA, Ericsson M, Barnett RJ, Drumm C, Seth P, Bloch DB, Levitsky S,Cowan DB, McCully JD.
Am J Physiol Heart Circ Physiol. 2013 Apr 1;304(7):H966-82. doi: 10.1152/ajpheart.00883.2012. Epub 2013 Jan 25.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Pathogen, Parasite

Entamoeba histolytica exacerbates epithelial tight junction permeability and proinflammatory responses in Muc2(-/-) mice.
Kissoon-Singh V1, Moreau F, Trusevych E, Chadee K.
Am J Pathol. 2013 Mar;182(3):852-65. doi: 10.1016/j.ajpath.2012.11.035. Epub 2013 Jan 26.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Cancer, Inflammation

GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.
Chou J1, Lin JH, Brenot A, Kim JW, Provot S, Werb Z.
Nat Cell Biol. 2013 Feb;15(2):201-13. doi: 10.1038/ncb2672. Epub 2013 Jan 27.


Assay Services Used: Human Cytokine Array 15-Plex
Disease / Biomarker Category: Immunology, T Cells, Virology

Comparison of the effect of standard and novel immunosuppressive drugson CMV-specific T-cell cytokine profiling.
Egli A1, Kumar D, Broscheit C, O’Shea D, Humar A.
Transplantation. 2013 Feb 15;95(3):448-55. doi: 10.1097/TP.0b013e318276a19f.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Bone, Pollution, Immunology

Exposure to urban air pollution and bone health in clinically healthy six-year-old children.
Calderón-Garcidueñas L1, Mora-Tiscareño A, Francolira M, Torres-Jardón R, Peña-Cruz B, Palacios-López C, Zhu H, Kong L, Mendoza-Mendoza N, Montesinoscorrea H, Romero L, Valencia-Salazar G, Kavanaugh M, Frenk S.
Arh Hig Rada Toksikol. 2013;64(1):23-34. doi: 10.2478/10004-1254-64-2013-2219.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Immunology, Pathogen

Bruton’s Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1 dependentphagocytosis of Candida albicans in macrophages.
Strijbis K1, Tafesse FG, Fairn GD, Witte MD, Dougan SK, Watson N, Spooner E, Esteban A, Vyas VK, Fink GR, Grinstein S, Ploegh HL.
PLoS Pathog. 2013;9(6):e1003446. doi: 10.1371/journal.ppat.1003446. Epub 2013 Jun 27.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Neurology

Mechanisms of pediatric cerebral arteriopathy: an inflammatory debate.
Mineyko A1, Kirton A.
Pediatr Neurol. 2013 Jan;48(1):14-23. doi: 10.1016/j.pediatrneurol.2012.06.021.


Assay Services Used: Human Cytokine Array Custom Assay, 20 Biomarker Multiplex
Disease / Biomarker Category: Immunology, Autoimmune

Rituximab for the treatment of patients with autoimmune hepatitis who are refractory or intolerant to standard therapy.
Burak KW1, Swain MG, Santodomingo-Garzon T, Lee SS, Urbanski SJ, Aspinall AI, Coffin CS, Myers RP.
Can J Gastroenterol. 2013;27(5):273-80.


Assay Services Used: Human Cytokine Array Discovery Assay, 65 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Liver

Blood cytokine, chemokine and gene expression in cholestasis patients with intractablepruritis treated with a molecular adsorbent recirculating system: a case series.
Lisboa LF1, Asthana S, Kremer A, Swain M, Bagshaw SM, Gibney N, Karvellas CJ.
Can J Gastroenterol. 2012 Nov;26(11):799-805.


Assay Services Used: Human Cytokine Array, Custom 5-Plex
Disease / Biomarker Category: Cancer, Inflammation, Metabolism

Exercise and nutrition for head and neck cancer patients: a patientoriented, clinic-supported randomized controlled trial.
Capozzi LC1, Lau H, Reimer RA, McNeely M, Giese-Davis J, Culos-Reed SN.
BMC Cancer. 2012 Oct 2;12:446. doi: 10.1186/1471-2407-12-446.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Obesity, Respiratory System, Inflammation

Role of TNFR1 in the innate airway hyperresponsiveness of obese mice.
Zhu M1, Williams AS, Chen L, Wurmbrand AP, Williams ES, Shore SA.
J Appl Physiol (1985). 2012 Nov;113(9):1476-85. doi: 10.1152/japplphysiol.00588.2012. Epub 2012 Sep 13.


Assay Services Used: Rat Cytokine Array Discovery Assay, 27 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Nervous System

Immunoglobulin G (IgG) attenuates neuroinflammation and improves neurobehavioral recovery after cervical spinal cord injury.
Nguyen DH1, Cho N, Satkunendrarajah K, Austin JW, Wang J, Fehlings MG.
J Neuroinflammation. 2012 Sep 21;9:224. doi: 10.1186/1742-2094-9-224.


Assay Services Used: Human Cytokine Array Discovery Assay, 65 Biomarker Multiplex
Disease / Biomarker Category: Esophagus, Smooth Muscle

HCl-induced and ATP-dependent upregulation of TRPV1 receptor expression and cytokine production by human esophageal epithelial cells.
Ma J1, Altomare A, Guarino M, Cicala M, Rieder F, Fiocchi C, Li D, Cao W, Behar J, Biancani P, Harnett KM.
Am J Physiol Gastrointest Liver Physiol. 2012 Sep 1;303(5):G635-45.


Assay Services Used: Mouse Cytokine Array Discovery
Disease / Biomarker Category: Immunology, Cardiology

Decreased Krev interaction trapped 1 expression leads to increased vascular permeability and modifies inflammatory responses in vivo.
Corr M1, Lerman I, Keubel JM, Ronacher L, Misra R, Lund F, Sarelius IH, Glading AJ.
Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):2702-10. doi: 10.1161/ATVBAHA.112.300115. Epub 2012 Aug 23.


Assay Services Used: Human Cytokine Array Discovery Assay, 65 Biomarker Multiplex
Disease / Biomarker Category: Stroke, Inflammation, Cytokines, Chemokines

Inflammatory biomarkers of pediatric focal cerebral arteriopathy.
Mineyko A, Narendran A, Fritzler ML, Wei X, Schmeling H, Kirton A.
Neurology 2012, epub Aug 22.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Cancer, Stem Cell, B-cell

Context-specific roles for paracrine IL-6 in lymphomagenesis.
Gilbert LA, Hemann MT.
Genes Dev. 2012 Aug 1;26(15):1758-68. doi: 10.1101/gad.197590.112.


Assay Services Used: Human Cytokine Array Discovery Assay, 41 Biomarker Multiplex
Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology, Allergy

Murine but not human basophil undergoes cell-specific proteolysis of a major endoplasmic reticulum chaperone.
Liu B, Staron M, Li Z.
PLoS One. 2012;7(6):e39442. doi: 10.1371/journal.pone.0039442. Epub 2012 Jun 18.


Assay Services Used: Human MMP & TIMP Discovery assay
Disease / Biomarker Category: Arthritis, Inflammation

Matrix metalloproteinase protein expression profiles cannot distinguish between normal and early osteoarthritic synovial fluid.
Heard BJ1, Martin L, Rattner JB, Frank CB, Hart DA, Krawetz R.
BMC Musculoskelet Disord. 2012 Jul 23;13:126. doi: 10.1186/1471-2474-13-126.


Assay Services Used: Human Cancer Array
Disease / Biomarker Category: Cancer, Inflammation, Colon Cancer

Epidermal growth factor receptor transactivation is required for proteinase-activated receptor-2-induced COX-2 expression in intestinal epithelial cells.
Hirota CL, Moreau F, Iablokov V, Dicay M, Renaux B, Hollenberg MD, MacNaughton WK.
Am J Physiol Gastroint Liver Physiol. 2012 Jul;303(1):G111-9. doi: 10.1152/ajpgi.00358.2011.


Assay Services Used: Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease / Biomarker Category: Immunology, Nanoparticles, Drug Delivery

Synthesis and characterization of novel zwitterionic lipids with pH-responsive biophysical properties.
Walsh CL1, Nguyen J, Szoka FC.
Chem Commun (Camb). 2012 Jun 7;48(45):5575-7. doi: 10.1039/c2cc31710a.
Authors did not specify Eve Tech generated data.


Assay Services Used: Human Cytokine Array, 4 Biomarker Custom Multiplex
Disease / Biomarker Category: Inflammation, COPD

Effect of incremental exercise on airway and systemic inflammation in patients with COPD.
Davidson WJ, Verity WS, Traves SL, Leigh R, Ford GT, Eves ND.
J Appl Physiol (1985). 2012 Jun;112(12):2049-56. doi: 10.1152/japplphysiol.01615.2011.
Authors did not specify Eve Tech generated data.


Assay Services Used: Rat Cytokine Array Discovery Assay, 27 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Nervous System, Arachnoiditis

The effects of intrathecal injection of a hyaluronan-based hydrogel on inflammation, scarring and neurobehavioural outcomes in a rat model of severe spinal cord injury associated with arachnoiditis.
Austin JW1, Kang CE, Baumann MD, DiDiodato L, Satkunendrarajah K, Wilson JR, Stanisz GJ, Shoichet MS, Fehlings MG.
Biomaterials. 2012 Jun;33(18):4555-64. doi: 10.1016/j.biomaterials.2012.03.022. Epub 2012 Mar 27.


Assay Services Used: Rat Metabolic Hormone Array Custom Assay – 4 Biomarker Multiplex
Disease / Biomarker Category: Gut Hormone, Diabetes

Block of Kv1.7 potassium currents increases glucose-stimulated insulin secretion.
Finol-Urdaneta R, Remedi M, Raasch W, Becker S, Clark R, Str�ver N, Pavlov E, Nichols C, French R, Terlau H.
EMBO Mol Med. 2012 May;4(5):424-34. doi: 10.1002/emmm.201200218. Epub 2012 Mar 21.


Assay Services Used: Human Cytokine Array Discovery Assay – 42 Biomarker Multiplex
Disease / Biomarker Category: Diabetes, Renal Inflammation, Cytokines, Chemokines

Urinary markers of renal inflammation in adolescents with Type 1 diabetes mellitus and normoalbuminuria.
Cherney D, Scholey J, Daneman D, Dunger D, Dalton R, Moineddin R, Mahmud F, Dekker R, Elia Y, Sochett E, Reich H.
Diabet Med. 2012 Mar 14. doi: 10.1111/j.1464-5491.2012.03651.x


Assay Services Used: Human Cytokine Array Discovery Assay – 42 Biomarker Multiplex
Disease / Biomarker Category: Rheumatoid Arthritis, Inflammation, Cytokines, Chemokines

Familial clustering of the serum cytokine profile in the relatives of rheumatoid arthritis patients.
El-Gabalawy H, Robinson D, Smolik I, Hart D, Elias B, Wong K, Peschken C, Hitchon C, Li X, Bernstein C, Newkirk M, Fritzler M.
Arthritis Rheum. 2012 Feb 21. doi: 10.1002/art.34449.


Assay Services Used: Rat Cytokine Array Discovery Assay – 23 Biomarker Multiplex
Disease / Biomarker Category: Intestine Microbiota, Myocardial Infarctions, Cytokines

Intestinal microbiota determine severity of myocardial infarction in rats.
Lam V, Su J, Koprowski S, Hsu A, Tweddell JS, Rafiee P, Gross GJ, Salzman NH, Baker JE.
FASEB J. 2012 Jan 12. [Epub ahead of print]


Assay Services Used: Human Cytokine Array Discovery Assay – 65 Biomarker Multiplex
Disease / Biomarker Category: Cancer, Cytokines, Chemokines, Growth Factors

Multi-tyrosine kinase inhibitors in preclinical studies for pediatric CNS AT/RT: Evidence for synergy with Topoisomerase-I inhibition.
Jayanthan A, Bernoux D, Bose P, Riabowol K, Narendran A.
Cancer Cell Int. 2011 Dec 29;11(1):44.
Authors did not specify Eve Tech generated data.


Assay Services Used: Mouse Cytokine Array Discovery Assay – 32 Biomarker Multiplex
Disease / Biomarker Category: Asthma, Allergy, Inflammation, Cytokines

Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation.
Arizmendi N, Abel M, Puttagunta L, Asaduzzaman M, Davidson C, Karimi K, Forsythe P, Vliagoftis H.
Allergy Asthma Clin Immunol. 2011 Dec 14;7:22.


Assay Services Used: Mouse Cytokine Array Discovery Assay – 22 Biomarker Multiplex
Disease / Biomarker Category: Colorectal Cancer, Cytokines, Chemokines

Smad4 deficiency in T cells leads to the Th17-associated development of premalignant gastroduodenal lesions in mice.
Hahn JN, Falck VG, Jirik FR.
J Clin Invest. 2011 Oct 3;121(10):4030-42. doi: 10.1172/JCI45114. Epub 2011 Sep 1


Assay Services Used: Rat Gut Hormone Custom Array Assay – 5 Biomarker Multiplex
Disease / Biomarker Category: Diet, Nutrition, Gut Hormones

Changes in Differential Functional Magnetic Resonance Signals in the Rodent Brain Elicited by Mixed-Nutrient or Protein-Enriched Meals.
Min DK, Tuor UI, Koopmans HS, Chelikani PK.
Gastroenterology. 2011 Jul 28.
Authors did not specify Eve Tech generated data.


Assay Services Used: Rat Gut Hormone Custom Array Assay – 8 Biomarker Multiplex
Disease / Biomarker Category: Diet, Nutrition, Gut Hormones

Prebiotic fibres dose-dependently increase satiety hormones and alter Bacteroidetes and Firmicutes in lean and obese JCR:LA-cp rats.
Parnell JA, Reimer RA.
Br J Nutr. 2011 Jul 18:1-13.
Authors did not specify Eve Tech generated data.


Assay Services Used: Mouse Cytokine Array Discovery Assay – 32 Biomarker Multiplex
Disease / Biomarker Category: Crohn’s Disease, Inflammation, Intestine Microbiota

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.
Hirota S, Ng J, Lueng A, Khajah M, Parhar K, Li Y, Lam V, Potentier MS, Ng K, Bawa M, McCafferty DM, Rioux KP, Ghosh S, Xavier RJ, Colgan SP, Tschopp J, Muruve D, MacDonald JA, Beck PL.
Inflamm Bowel Dis. 2011 Jun;17(6):1359-72. doi: 10.1002/ibd.21478. Epub 2010 Sep 24.
Authors did not specify Eve Tech generated data.


Assay Services Used: Human Cytokine Array Custom Assay – 10 Biomarker Multiplex
Disease / Biomarker Category: Gastrointestinal Systems, IFN?, Src, Cytokines

Interferon-?-induced increases in intestinal epithelial macromolecular permeability requires the Src kinase Fyn.
Smyth D, Phan V, Wang A, McKay DM.
Lab Invest. 2011 May;91(5):764-77. Epub 2011 Feb 14.
Authors did not specify Eve Tech generated data.


Assay Services Used: Custom Biomarker
Disease / Biomarker Category: Autoimmune

Historical perspectives on the discovery and elucidation of autoantibodies tocentromere protein(CENP) and the emerging importance of antibodies to CENP-F.
Fritzler MJ1, Rattner JB, Luft LM, Edworthy SM, Casiano CA, Peebles C, Mahler M.
Autoimmun Rev. 2011 Feb;10(4):194-200. doi: 10.1016/j.autrev.2010.09.025. Epub 2010 Oct 8.


Assay Services Used: Rat Gut Hormone Custom Array Assay – 8 Biomarker Multiplex
Disease / Biomarker Category: Diet, Nutrition, Gut Hormones

Maternal consumption of high-prebiotic fibre or -protein diets during pregnancy and lactation differentially influences satiety hormones and expression of genes involved in glucose and lipid metabolism in offspring in rats.
Maurer AD, Reimer RA.
Br J Nutr. 2011 Feb;105(3):329-38. Epub 2010 Dec 6.
Authors did not specify Eve Tech generated data.


Assay Services Used: Cytoplasmic-Dot Autoimmune Assay – 10 Biomarker Multiplex
Disease / Biomarker Category: Autoimmune Disease, GW bodies

Autoantibodies to GW bodies and other autoantigens in primary biliary cirrhosis.
Stinton LM, Swain M, Myers RP, Shaheen AA, Fritzler MJ.
Clin Exp Immunol. 2011 Feb;163(2):147-56. doi: 10.1111/j.1365-2249.2010.04288.x. Epub 2010 Nov 22.
Authors did not specify Eve Tech generated data.


Assay Services Used: Human Cytokine Array Discovery Assay – 42 Biomarker Multiplex
Disease / Biomarker Category: Diabetes, Urine Protein Analysis, Cytokines, Chemokines

The acute effect of clamped hyperglycemia on the urinary excretion of inflammatory cytokines/chemokines in uncomplicated type 1 diabetes: a pilot study.
Cherney DZ, Scholey JW, Sochett E, Bradley TJ, Reich HN.
Diabetes Care. 2011 Jan;34(1):177-80. Epub 2010 Sep 14.


Assay Services Used: Rat Gut Hormone Custom Array Assay – 8 Biomarker Multiplex
Disease / Biomarker Category: Diet, Nutrition, Gut Hormones

A High Calcium, Skim Milk Powder Diet Results in a Lower Fat Mass in Male, Energy-Restricted, Obese Rats More Than a Low Calcium, Casein, or Soy Protein Diet.
Eller LK, Reimer RA.
J Nutr. 2010 Jul;140(7):1234-41. Epub 2010 May 12.
Authors did not specify Eve Tech generated data.


Assay Services Used: Rat Gut Hormone Custom Array Assay – 8 Biomarker Multiplex
Disease / Biomarker Category: Diet, Nutrition, Gut Hormones

Consumption of Diets High in Prebiotic Fiber or Protein during Growth Influences the Response to a High Fat and Sucrose Diet in Adulthood in Rats.
Maurer AD, Eller LK, Hallam MC, Taylor K, Reimer RA.
Nutr Metab. 2010;7(1) © 2010 BioMed Central, Ltd.
Authors did not specify Eve Tech generated data.


Assay Services Used: Human Cytokine Array Discovery Assay – 42 Biomarker Multiplex
Assay Services Used: Human Bone Marker Panel Array – 8 Biomarker Multiplex
Assay Services Used: Human Matrix metalloproteinase (MMP) Array – 8 Biomarker Multiplex
Disease / Biomarker Category: Inflammation, Arthritis, Autoimmune, Cytokines, MMPs

Multiplex assay of a panel of 58 biomarkers in ankylosing spondylitis: identification of high priority candidates for prediction of structural damage.
Maksymowych WP, Morency N, Wichuk S, Rahman P, Gladman DD, Inman RD.
Ann Rheum Dis 69(suppl3):428, 2010.


Assay Services Used: Rat Gut Hormone Custom Array Assay – 8 Biomarker Multiplex
Disease / Biomarker Category: Diet, Nutrition, Gut Hormones

Long-term dietary restriction influences plasma ghrelin and GOAT mRNA level in rats.
Reimer RA, Maurer AD, Lau DC, Auer RN.
Physiol Behav. 2010 Apr 19;99(5):605-10. Epub 2010 Feb 9.
Authors did not specify Eve Tech generated data.


Assay Services Used: Rat Gut Hormone Custom Array Assay – 8 Biomarker Multiplex
Disease / Biomarker Category: Diet, Nutrition, Gut Hormones

Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults.
Parnell JA, Reimer RA.
Am J Clin Nutr. 2009 Jun;89(6):1751-9. Epub 2009 Apr 22.
Authors did not specify Eve Tech generated data.


Assay Services Used: Rat Gut Hormone Custom Array Assay – 8 Biomarker Multiplex
Disease / Biomarker Category: Diet, Nutrition, Gut Hormones

Changes in satiety hormones and expression of genes involved in glucose and lipid metabolism in rats weaned onto diets high in fibre or protein reflect susceptibility to increased fat mass in adulthood.
Maurer AD, Chen Q, McPherson C, Reimer RA.
J Physiol. 2009 Feb 1;587(Pt 3):679-91. Epub 2008 Dec 8.
Authors did not specify Eve Tech generated data.


Assay Services Used: ENA Profile
Disease / Biomarker Category: Autoimmune

Microbead-based technologies in diagnostic autoantibody detection.
Fritzler MJ, Fritzler ML.
Expert Opin Med Diagn. 2009 Jan;3(1):81-9. doi: 10.1517/17530050802651561.


Assay Services Used: Custom Peptide Array
Disease / Biomarker Category: Autoimmune

Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing.
Li S1, Lian SL, Moser JJ, Fritzler ML, Fritzler MJ, Satoh M, Chan EK.
J Cell Sci. 2008 Dec 15;121(Pt 24):4134-44. doi: 10.1242/jcs.036905.


Assay Services Used: Rat Gut Hormone Custom Array Assay – 8 Biomarker Multiplex
Disease / Biomarker Category: Diet, Nutrition, Gut Hormones

Differential responses of circulating amylin to high-fat vs. high-carbohydrate meal in healthy men.
Eller LK, Ainslie PN, Poulin MJ, Reimer RA.
Clin Endocrinol (Oxf). 2008 Jun;68(6):890-7. Epub 2007 Nov 19.
Authors did not specify Eve Tech generated data.


Assay Services Used: Cytoplasmic-Dot Autoimmune Assay – 10 Biomarker Multiplex
Disease / Biomarker Category: Autoimmune Disease, GW bodies

Clinical and serological features of patients with autoantibodies to GW/P bodies.
Bhanji RA1, Eystathioy T, Chan EK, Bloch DB, Fritzler MJ.
Clin Immunol. 2007 Dec;125(3):247-56. Epub 2007 Sep 17.


Assay Services Used: ENA Profile
Disease / Biomarker Category: Autoimmune

The emergence of multiplexed technologies as diagnostic platforms in systemic autoimmune diseases.
Fritzler MJ, Fritzler ML.
Curr Med Chem. 2006;13(21):2503-12. Review. PMID:17017907


Assay Services Used: ENA Profile
Disease / Biomarker Category: Autoimmune, Immunology

Analysis of human sera that are polyreactive in an addressable laser bead immunoassay.
Fritzler MJ1, Behmanesh F, Fritzler ML.
Clin Immunol. 2006 Sep;120(3):349-56. Epub 2006 Apr 27.


Assay Services Used: Custom Peptide Array
Disease / Biomarker Category: Autoimmune

Identification of the B-cell epitopes of the early endosome antigen 1 (EEA1).
Selak S1, Mahler M, Miyachi K, Fritzler ML, Fritzler MJ.
Clin Immunol. 2003 Nov;109(2):154-64.
Authors did not specify Eve Tech generated data.