Select Publications Involving Eve Technologies™

Eve Technologies has been cited in over 2,000 published articles. For the most up-to-date publications, visit Google Scholar and search “Eve Technologies”.

Assay Services Used:  Human Cytokine Array Discovery Assay, 71 Biomarker Multiplex
Disease/Biomarker Category:  Cytokine signaling patterns

Daniel J. Polley1, Penny Latham, May Y. Choi, Katherine A. Buhler, Marvin J. Fritzler, Mark L. Fritzler. Identification of novel clusters of co-expressing cytokines in a diagnostic cytokine multiplex test. doi: 10.3389/fimmu.2023.1223817.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Acute respiratory distress syndrome

Zhou Y, Li P, Goodwin AJ, Cook JA, Halushka PV, Chang E, Zingarelli B, Fan H. Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury. Crit Care. 2019 Feb 13;23(1):44. doi: 10.1186/s13054-019-2339-3.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Obesity, Cell cycle, Anxiety

Ogrodnik M, Zhu Y, Langhi LGP, Tchkonia T, Krüger P, Fielder E, Victorelli S, Ruswhandi RA, Giorgadze N, Pirtskhalava T, Podgorni O, Enikolopov G, Johnson KO, Xu M, Inman C, Palmer AK, Schafer M, Weigl M, Ikeno Y, Burns TC, Passos JF, von Zglinicki T, Kirkland JL, Jurk D. Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis. Cell Metab. 2019 Jan 3. pii: S1550-4131(18)30745-9. doi: 10.1016/j.cmet.2018.12.008.

Assay Services Used:  Human MMP & TIMP Discovery Assay
Disease/Biomarker Category: Cardiac physiology, Extracellular matrix dysfunction

Guzzardi DG, Teng G, Kang S, Geeraert PJ, Pattar SS, Svystonyuk DA, Belke DD, Fedak PWM. Induction of human aortic myofibroblast-mediated extracellular matrix dysregulation: A potential mechanism of fluoroquinolone-associated aortopathy. The J Thorac Cardiovasc Surg. 2019 Jan;157(1):109-119.e2. doi: 10.1016/j.jtcvs.2018.08.079.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Immunology, T-cell physiology, Chronic Infection

Xin G, Zander R, Schauder DM, Chen Y, Weinstein JS, Drobyski WR, Tarakanova V, Craft J, Cui W. Single-cell RNA sequencing unveils an IL-10-producing helper subset that sustains humoral immunity during persistent infection. Nat Commun. 2018 Nov 28;9(1):5037. doi: 10.1038/s41467-018-07492-4.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category:  Viral infection, T-Cell function

Varanasi SK, Rajasagi NK, Jaggi U, Rouse BT. Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions. Mucosal Immunol. 2018 Nov;11(6):1705-1715. doi: 10.1038/s41385-018-0058-8.

Assay Services Used:  Human Cytokine Array Discovery Assay, 65 Biomarker Multiplex
Disease/Biomarker Category: Cancer, Immunotherapy, Inflammation

Lim SY, Lee JH, Gide TN, Menzies AM, Guminski A, Carlino MS, Breen EJ, Yang JYH, Ghazanfar S, Kefford RF, Scolyer RA, Long GV, Rizos H. Circulating cytokines predict immune-related toxicity in melanoma patients receiving anti-PD-1-based immunotherapy. Clin Cancer Res. 2018 Nov 8. pii: clincanres.2795.2018. doi: 10.1158/1078-0432.CCR-18-2795.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Inflammation

Elling R, Robinson EK, Shapleigh B, Liapis SC, Covarrubias S, Katzman S, Groff AF, Jiang Z, Agarwal S, Motwani M5, Chan J, Sharma S, Hennessy EJ, FitzGerald GA, McManus MT, Rinn JL, Fitzgerald KA, Carpenter S. Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2. Cell Rep. 2018 Nov 6;25(6):1511-1524.e6. doi: 10.1016/j.celrep.2018.10.027.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Sepsis

Li P, Zhou Y, Goodwin AJ, Cook JA, Halushka PV, Zhang XK, Wilson CL, Schnapp LM, Zingarelli B, Fan H. Fli-1 Governs Pericyte Dysfunction in a Murine Model of Sepsis. J Infect Dis. 2018 Nov 5;218(12):1995-2005. doi: 10.1093/infdis/jiy451.

Assay Services Used:  Human Cytokine Array Discovery Assay, 42 Biomarker Multiplex
Assay Services Used:  Human Angiogenesis Array Discovery Assay, 17 Biomarker Multiplex
Disease/Biomarker Category: Cardiac physiology

Haglund TA, Rajasekaran NS, Smood B, Giridharan GA, Hoopes CW, Holman WL, Mauchley DC, Parbhu SD, Pamboukian SV, Tallaj JA, Rajapreyar IN, Kirklin JK, Sethu P. Evaluation of flow-modulation approaches in ventricular assist devices using an in-vitro endothelial cell culture model. J Heart Lung Transplant. 2018 Nov 2. pii: S1053-2498(18)31730-3. doi: 10.1016/j.healun.2018.10.007.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category:  Inflammation resolution

Smith TL, Van Slyke P, Jones N, Dumont DJ, McGlade CJ. Tie2 signalling through Erk1/2 regulates TLR4 driven inflammation. Cell Signal. 2018 Nov;51:211-221. doi: 10.1016/j.cellsig.2018.08.001.

Assay Services Used:  Human Focused Cytokine Array Discovery Assay, 13 Biomarker Multiplex
Disease/Biomarker Category: Entamoeba histolytica infection, Immunology, inflammation

Quach J, Moreau F, Sandall C, Chadee K. Entamoeba histolytica-induced IL-1β secretion is dependent on caspase-4 and gasdermin D. Mucosal Immunol. 2018 Oct 25. doi: 10.1038/s41385-018-0101-9.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Multiple Sclerosis, Microglial physiology

Acharjee S, Verbeek M, Gomez CD, Bisht K, Lee B, Benoit L, Sharkey KA, Benediktsson A, Tremblay ME, Pittman QJ. Reduced Microglial Activity and Enhanced Glutamate Transmission in the Basolateral Amygdala in Early CNS Autoimmunity. J Neurosci. 2018 Oct 17;38(42):9019-9033. doi: 10.1523/JNEUROSCI.0398-18.2018.

Assay Services Used:  Human Cytokine Array Discovery Assay, 42 Biomarker Multiplex
Disease/Biomarker Category:  Mesenchymal stem cell therapy

Russell AL, Lefavor RC, Zubair AC. Characterization and cost-benefit analysis of automated bioreactor-expanded mesenchymal stem cells for clinical applications. Transfusion. 2018 Oct;58(10):2374-2382. doi: 10.1111/trf.14805.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category:  Bacterial lung infection, Inflammasome function

Pires S, Parker D. IL-1β activation in response to Staphylococcus aureus lung infection requires inflammasome-dependent and independent mechanisms. Eur J Immunol. 2018 Oct;48(10):1707-1716. doi: 10.1002/eji.201847556.

Assay Services Used:  Mouse MMP Array Discovery Assay, 5 Biomarker Multiplex
Disease/Biomarker Category: Chronic pain, Neurology

Tajerian M, Hung V, Nguyen H, Lee G, Joubert LM, Malkovskiy AV, Zou B, Xie S, Huang TT, Clark JD. The hippocampal extracellular matrix regulates pain and memory after injury. Mol Psychiatry. 2018 Sep 26. doi: 10.1038/s41380-018-0209-z.

Assay Services Used:  Human Cytokine Array Discovery Assay, 65 Biomarker Multiplex
Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Assay Services Used:  Mouse Metabolic Hormone Array Discovery Assay, 11 Biomarker Multiplex
Disease/Biomarker Category:  Inflammation, Glucocorticoid function, Insulin resistance

Meng G, Tang X, Yang Z, Zhao Y, Curtis JM, McMullen TPW, Brindley DN. Dexamethasone decreases the autotaxin-lysophosphatidate-inflammatory axis in adipose tissue: implications for the metabolic syndrome and breast cancer. FASEB J. 2018 Sep 7:fj201801226R. doi: 10.1096/fj.201801226R.

Assay Services Used:  Human Cytokine Array
Disease/Biomarker Category:  Virology, Immunology

L’Huillier AG, Ferreira VH, Hirzel C, Cordero E, Limaye AP, Reid G, Englund J, Blumberg E, Kumar D, Humar A. Cytokine Profiles and Severity of Influenza Infection in Transplant Recipients. J Infect Dis. 2018 Sep 5. doi: 10.1093/infdis/jiy535.

Assay Services Used:  Human Focused Cytokine Array Discovery Assay, 11 Biomarker Multiplex
Disease/Biomarker Category:  Inflammation

Sloan RP, Shapiro PA, McKinley PS, Bartels M, Shimbo D, Lauriola V, Karmally W, Pavlicova M, Choi CJ, Choo TH, Scodes JM, Flood P, Tracey KJ. Aerobic Exercise Training and Inducible Inflammation: Results of a Randomized Controlled Trial in Healthy, Young Adults. J Am Heart Assoc. 2018 Sep 4;7(17):e010201. doi: 10.1161/JAHA.118.010201.

Assay Services Used:  Human Angiogenesis & Growth Factor Array, 17 Biomarker Multiplex
Disease/Biomarker Category:  Intestinal physiology, Wound healing

Tawiah A, Moreau F, Kumar M, Tiwari S, Falguera J, Chadee K. High MUC2 Mucin Biosynthesis in Goblet Cells Impedes Restitution and Wound Healing by Elevating Endoplasmic Reticulum Stress and Altered Production of Growth Factors. Am J Pathol. 2018 Sep;188(9):2025-2041. doi: 10.1016/j.ajpath.2018.05.013.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Gastrointestinal Physiology, Immunology

Flannigan KL, Taylor MR, Pereira SK, Rodriguez-Arguello J, Moffat AW, Alston L, Wang X, Poon KK, Beck PL, Rioux KP, Jonnalagadda M, Chelikani PK, Galipeau HJ, Lewis IA, Workentine ML, Greenway SC, Hirota SA. An intact microbiota is required for the gastrointestinal toxicity of the immunosuppressant mycophenolate mofetil. J Heart Lung Transplant. 2018 Sep;37(9):1047-1059. doi: 10.1016/j.healun.2018.05.002.

Assay Services Used:  Rat Cytokine Array Discovery Assay, 27 Biomarker Multiplex
Disease/Biomarker Category:  Critical illness myopathy, Glucocorticoid function, Skeletal muscle physiology

Akkad H, Cacciani N, Llano-Diez M, Corpeno Kalamgi R, Tchkonia T, Kirkland JL, Larsson L. Vamorolone treatment improves skeletal muscle outcome in a critical illness myopathy rat model. Acta Physiol (Oxf). 2018 Aug 18:e13172. doi: 10.1111/apha.13172.

Assay Services Used:  Human Cytokine Array Discovery Assay, 42 Biomarker Multiplex
Disease/Biomarker Category:  Inflammation, Cytokine release, Nuclear cytokine function

Travers J, Rochman M, Miracle CE, Habel JE, Brusilovsky M, Caldwell JM, Rymer JK, Rothenberg ME. Chromatin regulates IL-33 release and extracellular cytokine activity. Nat Commun. 2018 Aug 14;9(1):3244. doi: 10.1038/s41467-018-05485-x.

Assay Services Used:  Rat Cytokine Single Plex Custom Assay
Disease/Biomarker Category:  Arthritis, Pain, Microglial function

Mousseau M, Burma NE, Lee KY, Leduc-Pessah H, Kwok CHT, Reid AR, O’Brien M, Sagalajev B, Stratton JA, Patrick N, Stemkowski PL, Biernaskie J, Zamponi GW, Salo P, McDougall JJ, Prescott SA, Matyas JR, Trang T. Microglial pannexin-1 channel activation is a spinal determinant of joint pain. Sci Adv. 2018 Aug 8;4(8):eaas9846. doi: 10.1126/sciadv.aas9846.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category:  Degenerative cervical myelopathy, Glucocorticoid function

Vidal PM, Ulndreaj A, Badner A, Hong J, Fehlings MG. Methylprednisolone treatment enhances early recovery following surgical decompression for degenerative cervical myelopathy without compromise to the systemic immune system. J Neuroinflamm. 2018 Aug 6;15(1):222. doi: 10.1186/s12974-018-1257-7.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Assay Services Used:  Human Cytokine Array Discovery Assay, 13 Biomarker Multiplex
Disease/Biomarker Category:  Engineered T-Cells, Tumor therapy

Helsen CW, Hammill JA, Lau VWC, Mwawasi KA, Afsahi A, Bezverbnaya K, Newhook L, Hayes DL, Aarts C, Bojovic B, Denisova GF, Kwiecien JM, Brain I, Derocher H, Milne K, Nelson BH, Bramson JL. The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity. Nat Commun. 2018 Aug 3;9(1):3049. doi: 10.1038/s41467-018-05395-y.

Assay Services Used:  Human Cytokine Array
Disease/Biomarker Category:  Aging, Cellular senescence, Senolytic therapy

Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Senolytics improve physical function and increase lifespan in old age. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Cancer, Immunology

Ghaffari A, Peterson N, Khalaj K, Vitkin N, Robinson A, Francis JA, Koti M. STING agonist therapy in combination with PD-1 immune checkpoint blockade enhances response to carboplatin chemotherapy in high-grade serous ovarian cancer. Br J Cancer. 2018 Aug;119(4):440-449. doi: 10.1038/s41416-018-0188-5.

Assay Services Used:  Rat Cytokine Array Discovery Assay, 27 Biomarker Multiplex
Assay Services Used:  Rat Vascular Injury Array Featured Assay
Disease/Biomarker Category:  Spinal cord injuries, Inflammation

Hong J, Chang A, Zavvarian MM, Wang J, Liu Y, Fehlings MG. Level-Specific Differences in Systemic Expression of Pro- and Anti-Inflammatory Cytokines and Chemokines after Spinal Cord Injury. Int J Mol Sci. 2018 Jul 25;19(8). pii: E2167. doi: 10.3390/ijms19082167.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Methicillin-Resistant Staphylococcus aureus Infection

Pires S, Jacquet R, Parker D. Inducible Costimulator Contributes to Methicillin-Resistant Staphylococcus aureus Pneumonia. J Infect Dis. 2018 Jul 13;218(4):659-668. doi: 10.1093/infdis/jix664.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Norovirus infection

Seamons A, Treuting PM, Meeker S, Hsu C, Paik J, Brabb T, Escobar SS, Alexander JS, Ericsson AC, Smith JG, Maggio-Price L. Obstructive Lymphangitis Precedes Colitis in Murine Norovirus-Infected Stat1-Deficient Mice. Am J Pathol. 2018 Jul;188(7):1536-1554. doi: 10.1016/j.ajpath.2018.03.019.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category:  Cancer, Exocrine dysfunction, Tissue wasting

Danai LV, Babic A, Rosenthal MH, Dennstedt EA, Muir A, Lien EC, Mayers JR, Tai K, Lau AN, Jones-Sali P, Prado CM, Petersen GM, Takahashi N, Sugimoto M, Yeh JJ, Lopez N, Bardeesy N, Fernandez-Del Castillo C, Liss AS, Koong AC, Bui J, Yuan C, Welch MW, Brais LK, Kulke MH, Dennis C, Clish CB, Wolpin BM, Vander Heiden MG. Altered exocrine function can drive adipose wasting in early pancreatic cancer. Nature. 2018 Jun;558(7711):600-604. doi: 10.1038/s41586-018-0235-7.

Assay Services Used:  Mouse Focused Cytokine Array Discovery Assay, 10 Biomarker Multiplex
Disease/Biomarker Category: Sepsis

Zhou Y, Li P, Goodwin AJ, Cook JA, Halushka PV, Chang E, Fan H. Exosomes from Endothelial Progenitor Cells Improve the Outcome of a Murine Model of Sepsis. Mol Ther. 2018 May 2;26(5):1375-84.

Assay Services Used:  Human Cytokine Array
Disease/Biomarker Category: Cancer

Wrangle JM, Velcheti V, Patel MR, Garrett-Mayer E, Hill EG, Ravenel JG, Miller JS, Farhad M, Anderton K, Lindsey K, Taffaro-Neskey M, Sherman C, Suriano S, Swiderska-Syn M, Sion A, Harris J, Edwards AR, Rytlewski JA, Sanders CM, Yusko EC, Robinson MD, Krieg C, Redmond WL, Egan JO, Rhode PR, Jeng EK, Rock AD, Wong HC, Rubinstein MP. ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial. The Lancet Oncol. 2018 May;19(5):694-704. doi: 10.1016/S1470-2045(18)30148-7.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Asthma, Allergic inflammation

Sehmi R, Lim HF, Mukherjee M, Huang C, Radford K, Newbold P, Boulet LP, Dorscheid D, Martin JG, Nair P. Benralizumab attenuates airway eosinophilia in prednisone-dependent asthma. J Allergy Clin Immunol. 2018 Apr;141(4):1529-1532.e8. doi: 10.1016/j.jaci.2018.01.008..

Assay Services Used:  Rat Cytokine Array Discovery Assay, 27 Biomarker Multiplex
Disease/Biomarker Category: Muscle Wasting

Salah H, Fury W, Gromada J, Bai Y, Tchkonia T, Kirkland JL, Larsson L. Muscle‐specific differences in expression and phosphorylation of the Janus kinase 2/Signal Transducer and Activator of Transcription 3 following long‐term mechanical ventilation and immobilization in rats. Acta Physiologica. 2018 Mar;222(3):e12980.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Cancer, Immunotherapy

Bazett M, Costa AM, Bosiljcic M, Anderson RM, Alexander MP, Wong SW, Dhanji S, Chen JM, Pankovich J, Lam S, Sutcliffe S. Harnessing innate lung anti-cancer effector functions with a novel bacterial-derived immunotherapy. OncoImmunology. 2018 Mar 4;7(3):e1398875.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Alzheimer’s Disease

Hou Y, Lautrup S, Cordonnier S, Wang Y, Croteau DL, Zavala E, Zhang Y, Moritoh K, O’Connell JF, Baptiste BA, Stevnsner TV, Mattson MP, Bohr VA.. NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1876-E1885. doi: 10.1073/pnas.1718819115.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Neurology

Plemel JR, Michaels NJ, Weishaupt N, Caprariello AV, Keough MB, Rogers JA, Yukseloglu A, Lim J, Patel VV, Rawji KS, Jensen SK. Mechanisms of lysophosphatidylcholine‐induced demyelination: A primary lipid disrupting myelinopathy. Glia. 2018 Feb;66(2):327-347. doi: 10.1002/glia.23245.

Assay Services Used:  Mouse Focused Cytokine Array Discovery Assay, 10 Biomarker Multiplex
Disease/Biomarker Category: Lung Fibrotic Disease, Immunology

Kim JH, Podstawka J, Lou Y, Li L, Lee EK, Divangahi M, Petri B, Jirik FR, Kelly MM, Yipp BG. Aged polymorphonuclear leukocytes cause fibrotic interstitial lung disease in the absence of regulation by B cells. Nat Immunol. 2018 Feb;19(2):192-201. doi: 10.1038/s41590-017-0030-x.

Assay Services Used:  Human Cytokine Array
Disease/Biomarker Category: Cancer

Chan JS, Sng MK, Teo ZQ, Chong HC, Twang JS, Tan NS. Targeting nuclear receptors in cancer-associated fibroblasts as concurrent therapy to inhibit development of chemoresistant tumors. Oncogene. 2018 Jan 11;37(2):160-173. doi: 10.1038/onc.2017.319.

Assay Services Used:  Human Interferon-β Custom 1-Plex Assay
Disease/Biomarker Category: Cancer

Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, Genovese G, Venkatesan S, Birkbak NJ, McGranahan N, Lundquist M, LaPlant Q, Healey JH, Elemento O, Chung CH, Lee NY, Imielenski M, Nanjangud G, Pe’er D, Cleveland DW, Powell SN, Lammerding J, Swanton C, Cantley LC. Chromosomal instability drives metastasis through a cytosolic DNA response. Nature. 2018 Jan 25;553(7689):467-472. doi: 10.1038/nature25432.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Neuroinflammation, Microglia

Mathur V, Burai R, Vest RT, Bonanno LN, Lehallier B, Zardeneta ME, Mistry KN, Do D, Marsh SE, Abud EM, Blurton-Jones M. Activation of the STING-dependent type I interferon response reduces microglial reactivity and neuroinflammation. Neuron. 2017 Dec 20;96(6):1290-302.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 44 Biomarker Multiplex
Assay Services Used:  Human Cytokine Array
Disease/Biomarker Category: Endometriosis

Miller JE, Monsanto SP, Ahn SH, Khalaj K, Fazleabas AT, Young SL, Lessey BA, Koti M, Tayade C. Interleukin-33 modulates inflammation in endometriosis. Scientific reports. 2017 Dec 20;7(1):17903.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Assay Services Used:  Human Focused Cytokine Array Discovery Assay, 13 Biomarker Multiplex
Disease/Biomarker Category: Bacterial Infection, Airway Physiology

Riquelme SA, Hopkins BD, Wolfe AL, DiMango E, Kitur K, Parsons R, Prince A. Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity. Immunity. 2017 Dec 19;47(6):1169-81.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Inflammation

Muku GE, Lahoti TS, Murray IA, Podolsky MA, Smith KJ, Hubbard TD, Kuzu G, Gowda K, Amin SG, Perdew GH. Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses. Lab Invest. 2017 Dec;97(12):1471-1487. doi: 10.1038/labinvest.2017.92.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Sepsis

Joachim R, Suber F, Kobzik L. Characterising Pre-pubertal Resistance to Death from Endotoxemia. Scientific reports. 2017 Nov 29;7(1):16541.

Assay Services Used:  Human Angiogenesis & Growth Factor Array Discovery Assay, 17 Biomarker Multiplex
Disease/Biomarker Category: Cancer

Oweida A, Sabri S, Al-Rabea A, Ebrahimi M, Ruo R, Fraser R, Seuntjens J, Abdulkarim B. Response to stereotactic ablative radiotherapy in a novel orthotopic model of non-small cell lung cancer. Oncotarget. 2017 Nov 28;9(2):1630-1640. doi: 10.18632/oncotarget.22727.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Viral Infection, T-Cell physiology

Bagri P, Anipindi VC, Nguyen PV, Vitali D, Stämpfli MR, Kaushic C. Novel Role for Interleukin-17 in Enhancing Type 1 Helper T Cell Immunity in the Female Genital Tract following Mucosal Herpes Simplex Virus 2 Vaccination. J Virol. 2017 Nov 14;91(23). pii: e01234-17. doi: 10.1128/JVI.01234-17.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 13 Biomarker Multiplex
Assay Services Used:  Human Focused Cytokine Array Discovery Assay, 13 Biomarker Multiplex
Disease/Biomarker Category: HIV infection

Nguyen PV, Wessels JM, Mueller K, Vahedi F, Anipindi V, Verschoor CP, Chew M, Deshiere A, Karniychuk U, Mazzulli T, Tremblay MJ. Frequency of Human CD45+ Target Cells is a Key Determinant of Intravaginal HIV-1 Infection in Humanized Mice. Scientific reports. 2017 Nov 10;7(1):15263.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category:  Parasite infection

Amat CB, Motta JP, Fekete E, Moreau F, Chadee K, Buret AG. Cysteine Protease–Dependent Mucous Disruptions and Differential Mucin Gene Expression in Giardia duodenalis Infection. Am J Pathol. 2017 Nov 1;187(11):2486-98.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Pain, Colitis

Basso L, Lapointe TK, Iftinca M, Marsters C, Hollenberg MD, Kurrasch DM, Altier C. Granulocyte-colony–stimulating factor (G-CSF) signaling in spinal microglia drives visceral sensitization following colitis. Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11235-40.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Fibrosis

Ayaub EA, Dubey A, Imani J, Botelho F, Kolb MR, Richards CD, Ask K. Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis. Scientific Reports. 2017 Oct 16;7(1):13281.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Aging, Inflammation

Laflamme C, Mailhot GB, Pouliot M. Age-related decline of the acute local inflammation response: a mitigating role for the adenosine A2A receptor. Aging (Albany NY). 2017 Oct;9(10):2083.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Cancer, Immunotherapy

Xu C, Zhang Y, Rolfe PA, Hernández VM, Guzman W, Kradjian G, Marelli B, Qin G, Qi J, Wang H, Yu H, Tighe R, Lo KM, English JM, Radvanyi L, Lan Y. Combination Therapy with NHS-muIL12 and Avelumab (anti-PD-L1) Enhances Antitumor Efficacy in Preclinical Cancer Models. Clin Cancer Res. 2017 Oct 1;23(19):5869-5880. doi: 10.1158/1078-0432.CCR-17-0483.

Assay Services Used:  Human Focused Cytokine Array Discovery Assay, 13 Biomarker Multiplex
Disease/Biomarker Category:  Pregnancy, Inflammation

Monsanto SP, Daher S, Ono E, Pendeloski KPT, Trainá É, Mattar R, Tayade C. Cervical cerclage placement decreases local levels of proinflammatory cytokines in patients with cervical insufficiency. Am J Obstet Gynecol. 2017 Oct;217(4):455.e1-455.e8. doi: 10.1016/j.ajog.2017.06.024.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Nasopharyngeal Infection, T-Cell

Zeppa JJ, Kasper KJ, Mohorovic I, Mazzuca DM, Haeryfar SM, McCormick JK. Nasopharyngeal infection by Streptococcus pyogenes requires superantigen-responsive Vβ-specific T cells. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10226-31.

Assay Services Used:  Rat Cytokine Array Discovery Assay, 27 Biomarker Multiplex
Assay Services Used:  Human Cytokine Array Discovery Assay, 65 Biomarker Multiplex
Disease/Biomarker Category:  Cancer, Radiation therapy

Meng G, Tang X, Yang Z, Benesch MGK, Marshall A, Murray D, Hemmings DG, Wuest F, McMullen TPW, Brindley DN. Implications for breast cancer treatment from increased autotaxin production in adipose tissue after radiotherapy. FASEB J. 2017 Sep;31(9):4064-4077. doi: 10.1096/fj.201700159R.

Assay Services Used:  Human Cytokine Array
Disease/Biomarker Category:  Gut microbiota, Obesity

Nicolucci AC, Hume MP, Martínez I, Mayengbam S, Walter J, Reimer RA. Prebiotics Reduce Body Fat and Alter Intestinal Microbiota in Children Who Are Overweight or With Obesity. Gastroenterology. 2017 Sep;153(3):711-722. doi: 10.1053/j.gastro.2017.05.055.

Assay Services Used:  Mouse/Rat Metabolic Hormone Array Discovery Assay, 11 Biomarker Multiplex
Disease/Biomarker Category: Obesity, Metabolism

Zapata RC, Singh A, Pezeshki A, Nibber T, Chelikani PK. Whey Protein Components-Lactalbumin and Lactoferrin-Improve Energy Balance and Metabolism. Scientific reports. 2017 Aug 30;7(1):9917.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Cancer, T-Cell physiology

Kim DS, Dastidar H, Zhang C, Zemp FJ, Lau K, Ernst M, Rakic A, Sikdar S, Rajwani J, Naumenko V, Balce DR. Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms. Nat Commun. 2017 Aug 24;8(1):344. doi: 10.1038/s41467-017-00324-x.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Multiple Sclerosis

Faissner S, Mahjoub Y, Mishra M, Haupeltshofer S, Hahn JN, Gold R, Koch M, Metz LM, Ben-Hur T, Yong VW. Unexpected additive effects of minocycline and hydroxychloroquine in models of multiple sclerosis: Prospective combination treatment for progressive disease?. Multiple Sclerosis Journal. 2017 Aug 1:1352458517728811.

Assay Services Used:  Human Cytokine Array Discovery Assay, 42 Biomarker Multiplex
Disease/Biomarker Category:  Diabetes, Renal physiology

Lovshin JA, Rajasekeran H, Lytvyn Y, Lovblom LE, Khan S, Alemu R, Locke A, Lai V, He H, Hittle L, Wang W, Drucker DJ, Cherney DZI. Dipeptidyl Peptidase 4 Inhibition Stimulates Distal Tubular Natriuresis and Increases in Circulating SDF-1α1-67 in Patients With Type 2 Diabetes. Diabetes Care. 2017 Aug;40(8):1073-1081. doi: 10.2337/dc17-0061.

Assay Services Used:  Mouse Cytokine Array, Custom 12-Plex
Disease/Biomarker Category:  Endometriosis

Khalaj K, Ahn SH, Bidarimath M, Nasirzadeh Y, Singh SS, Fazleabas AT, Young SL, Lessey BA, Koti M, Tayade C. A balancing act: RNA binding protein HuR/TTP axis in endometriosis patients. Scientific Reports. 2017 Jul 19;7(1):5883.

Assay Services Used:  Human Cytokine Array Discovery Assay, 42 Biomarker Multiplex
Disease/Biomarker Category:  Diabetes

Lytvyn Y, Har R, Locke A, Lai V, Fong D, Advani A, Perkins BA, Cherney DZI. Renal and Vascular Effects of Uric Acid Lowering in Normouricemic Patients With Uncomplicated Type 1 Diabetes. Diabetes. 2017 Jul;66(7):1939-1949. doi: 10.2337/db17-0168.

Assay Services Used:  Human Cytokine Array
Disease/Biomarker Category:  Immunology

Singha S, Shao K, Yang Y, Clemente-Casares X, Solé P, Clemente A, Blanco J, Dai Q, Song F, Liu SW, Yamanouchi J, Umeshappa CS, Nanjundappa RH, Detampel P, Amrein M, Fandos C, Tanguay R, Newbigging S, Serra P, Khadra A, Chan WCW, Santamaria P. Peptide-MHC-based nanomedicines for autoimmunity function as T-cell receptor microclustering devices. Nat Nanotechnol. 2017 Jul;12(7):701-710. doi: 10.1038/nnano.2017.56.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Autoimmunity, Multiple Sclerosis

Rogers JA, Mishra MK, Hahn J, Greene CJ, Yates RM, Metz LM, Yong VW. Gestational bisphenol-A exposure lowers the threshold for autoimmunity in a model of multiple sclerosis. Proc Natl Acad Sci U S A. 2017 May 9;114(19):4999-5004. doi: 10.1073/pnas.1620774114.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Immunology, Cancer

Zhang J, Liu D, Li G, Staveley-O’Carroll KF, Graff JN, Li Z, Wu JD.. Antibody-mediated neutralization of soluble MIC significantly enhances CTLA4 blockade therapy. Sci Adv. 2017 May 17;3(5):e1602133. doi: 10.1126/sciadv.1602133.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Gut microbiota

Leclercq S, Mian FM, Stanisz AM, Bindels LB, Cambier E, Ben-Amram H, Koren O, Forsythe P, Bienenstock J. Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior. Nat Commun. 2017 Apr 4;8:15062. doi: 10.1038/ncomms15062.

Assay Services Used:  Human Adipokine Array Discover Assay, 5 Biomarker Multiplex
Disease/Biomarker Category:  Gut microbiota, Obesity

Hume MP, Nicolucci AC, Reimer RA. Prebiotic supplementation improves appetite control in children with overweight and obesity: a randomized controlled trial. Am J Clin Nutr. 2017 Apr;105(4):790-799. doi: 10.3945/ajcn.116.140947.

Assay Services Used:  Human Cytokine Array
Disease/Biomarker Category:  Staphylococcus aureus infection

Wickersham M, Wachtel S, Wong Fok Lung T, Soong G, Jacquet R, Richardson A, Parker D, Prince A. Metabolic Stress Drives Keratinocyte Defenses against Staphylococcus aureus Infection. Cell Rep. 2017 Mar 14;18(11):2742-2751. doi: 10.1016/j.celrep.2017.02.055.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Toxic shock syndrome

Szabo PA, Rudak PT, Choi J, Xu SX, Schaub R, Singh B, McCormick JK, Haeryfar SMM. Invariant Natural Killer T Cells Are Pathogenic in the HLA-DR4-Transgenic Humanized Mouse Model of Toxic Shock Syndrome and Can Be Targeted to Reduce Morbidity. J Infect Dis. 2017 Mar 1;215(5):824-829. doi: 10.1093/infdis/jiw646.

Assay Services Used:  Human Cytokine Array
Disease/Biomarker Category:  Allergy, Asthma, Eosinophil function

Mitchell PD, Salter BM, Oliveria JP, El-Gammal A, Tworek D, Smith SG, Sehmi R, Gauvreau GM, Butler M, O’Byrne PM. Glucagon-like peptide-1 receptor expression on human eosinophils and its regulation of eosinophil activation. Clin Exp Allergy. 2017 Mar;47(3):331-338. doi: 10.1111/cea.12860.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Cancer, Immunology

Murakami S, Shahbazian D, Surana R, Zhang W, Chen H, Graham GT, White SM, Weiner LM, Yi C. Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma. Oncogene. 2017 Mar 2;36(9):1232-1244. doi: 10.1038/onc.2016.288.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Spinal muscular atrophy, Immunology

Deguise MO, De Repentigny Y, McFall E, Auclair N, Sad S, Kothary R. Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice. Hum Mol Genet. 2017 Feb 15;26(4):801-819. doi: 10.1093/hmg/ddw434.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Cancer, Inflammation

Tang X, Wang X, Zhao YY, Curtis JM, Brindley DN. Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-κB activation. Mol Cancer. 2017 Feb 8;16(1):36. doi: 10.1186/s12943-017-0607-x.

Assay Services Used:  Human Cytokine & Adipokine Arrays
Disease/Biomarker Category:  Obesity, Gut microbiota, Nutrition

Lambert JE, Parnell JA, Tunnicliffe JM, Han J, Sturzenegger T, Reimer RA. Consuming yellow pea fiber reduces voluntary energy intake and body fat in overweight/obese adults in a 12-week randomized controlled trial. Clin Nutr. 2017 Feb;36(1):126-133. doi: 10.1016/j.clnu.2015.12.016.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Assay Services Used:  TGF-β Array Discovery Assay, 3 Biomarker Multiplex
Disease/Biomarker Category:  Inflammation, Macrophage function

Hsieh JY, Smith TD, Meli VS, Tran TN, Botvinick EL, Liu WF. Differential regulation of macrophage inflammatory activation by fibrin and fibrinogen. Acta Biomater. 2017 Jan 1;47:14-24. doi: 10.1016/j.actbio.2016.09.024

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Neuroinflammation

Torre S, Polyak MJ, Langlais D, Fodil N, Kennedy JM, Radovanovic I, Berghout J, Leiva-Torres GA, Krawczyk CM, Ilangumaran S, Mossman K, Liang C, Knobeloch KP, Healy LM, Antel J, Arbour N, Prat A, Majewski J, Lathrop M, Vidal SM, Gros P. USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation. Nat Immunol. 2017 Jan;18(1):54-63. doi: 10.1038/ni.3581.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Immunotherapy, Cancer

Lawson KA, Mostafa AA, Shi ZQ, Spurrell J, Chen W, Kawakami J, Gratton K, Thakur S, Morris DG. Repurposing Sunitinib with Oncolytic Reovirus as a Novel Immunotherapeutic Strategy for Renal Cell Carcinoma. Clin Cancer Res. 2016 Dec 1;22(23):5839-5850.

Assay Services Used:  Human Cytokine Array Discovery Assay, 42 Biomarker Multiplex
Disease/Biomarker Category: Inflammation, Cardiovascular disease

Pope CA 3rd, Bhatnagar A, McCracken JP, Abplanalp W, Conklin DJ, O’Toole T. Exposure to Fine Particulate Air Pollution Is Associated With Endothelial Injury and Systemic Inflammation. Circ Res. 2016 Nov 11;119(11):1204-1214. doi: 10.1161/CIRCRESAHA.116.309279.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Allergic airway disease

Bazett M, Biala A, Huff RD, Bosiljcic M, Gunn H, Kalyan S, Hirota JA. A novel microbe-based treatment that attenuates the inflammatory profile in a mouse model of allergic airway disease. Sci Rep. 2016 Oct 13;6:35338. doi: 10.1038/srep35338.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Crohn’s disease, Gastroenteritis

Small CL, Xing L, McPhee JB, Law HT, Coombes BK. Acute Infectious Gastroenteritis Potentiates a Crohn’s Disease Pathobiont to Fuel Ongoing Inflammation in the Post-Infectious Period. PLoS Pathog. 2016 Oct 6;12(10):e1005907. doi: 10.1371/journal.ppat.1005907.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Neurodegenerative disease, Inflammation

Livne-Bar I, Lam S, Chan D, Guo X, Askar I, Nahirnyj A, Flanagan JG, Sivak JM. Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis. Cell Death Dis. 2016 Sep 29;7(9):e2386. doi: 10.1038/cddis.2016.277.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Leukocyte physiology, Inflammation

Bajrami B, Zhu H, Kwak HJ, Mondal S, Hou Q, Geng G, Karatepe K, Zhang YC, Nombela-Arrieta C, Park SY, Loison F, Sakai J, Xu Y, Silberstein LE, Luo HR. G-CSF maintains controlled neutrophil mobilization during acute inflammation by negatively regulating CXCR2 signaling. J Exp Med. 2016 Sep 19;213(10):1999-2018. doi: 10.1084/jem.20160393.

Assay Services Used:  Human ANP ELISA
Disease/Biomarker Category: Type II Diabetes, Cardiovascular function

Heerspink HJ, Perkins BA, Fitchett DH, Husain M, Cherney DZ. Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes Mellitus: Cardiovascular and Kidney Effects, Potential Mechanisms, and Clinical Applications. Circulation. 2016 Sep 6;134(10):752-72. doi: 10.1161/CIRCULATIONAHA.116.021887.

Assay Services Used:  Human Cytokine Array
Disease/Biomarker Category: Diabetic kidney disease

Pedigo CE, Ducasa GM, Leclercq F, Sloan A, Mitrofanova A, Hashmi T, Molina-David J, Ge M, Lassenius MI, Forsblom C, Lehto M, Groop PH, Kretzler M, Eddy S, Martini S, Reich H, Wahl P, Ghiggeri G, Faul C, Burke GW 3rd, Kretz O, Huber TB, Mendez AJ, Merscher S, Fornoni A. Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury. J Clin Invest. 2016 Sep 1;126(9):3336-50. doi: 10.1172/JCI85939.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Skin infection, Necroptosis

Kitur K, Wachtel S, Brown A, Wickersham M, Paulino F, Peñaloza HF, Soong G, Bueno S, Parker D, Prince A. Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling. Cell Rep. 2016 Aug 23;16(8):2219-2230. doi: 10.1016/j.celrep.2016.07.039.

Assay Services Used:  Mouse and Human Cytokine Arrays
Disease/Biomarker Category:  Inflammation

Bent EH, Gilbert LA, Hemann MT. A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses. Genes Dev. 2016 Aug 15;30(16):1811-21. doi: 10.1101/gad.284851.116.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Inflammation, Cell signaling

Shim H, Wu C, Ramsamooj S, Bosch KN, Chen Z, Emerling BM, Yun J, Liu H, Choo-Wing R, Yang Z, Wulf GM, Kuchroo VK, Cantley LC. Deletion of the gene Pip4k2c, a novel phosphatidylinositol kinase, results in hyperactivation of the immune system. Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7596-601. doi: 10.1073/pnas.1600934113.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Inflammation

Atianand MK, Hu W, Satpathy AT, Shen Y, Ricci EP, Alvarez-Dominguez JR, Bhatta A, Schattgen SA, McGowan JD, Blin J, Braun JE, Gandhi P, Moore MJ, Chang HY, Lodish HF, Caffrey DR, Fitzgerald KA. A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation. Cell. 2016 Jun 16;165(7):1672-1685. doi: 10.1016/j.cell.2016.05.075.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Immunology, Macrophage polarization

Zhong TY, Arancibia S, Born R, Tampe R, Villar J, Del Campo M, Manubens A, Becker MI. Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages. J Immunol. 2016 Jun 1;196(11):4650-62. doi: 10.4049/jimmunol.1501156.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Autoimmune encephalomyelitis

Lévesque SA, Paré A, Mailhot B, Bellver-Landete V, Kébir H, Lécuyer MA, Alvarez JI, Prat A, de Rivero Vaccari JP, Keane RW, Lacroix S. Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice. J Exp Med. 2016 May 30;213(6):929-49. doi: 10.1084/jem.20151437.

Assay Services Used:  Human Cytokine Array Discovery Assay, 42 Biomarker Multiplex
Disease/Biomarker Category: Pemphigus vulgaris

Vodo D, Sarig O, Geller S, Ben-Asher E, Olender T, Bochner R, Goldberg I, Nosgorodsky J, Alkelai A, Tatarskyy P, Peled A, Baum S, Barzilai A, Ibrahim SM, Zillikens D, Lancet D, Sprecher E. Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene. PLoS Genet. 2016 May 5;12(5):e1006008. doi: 10.1371/journal.pgen.1006008.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category:  Cancer, Liver function, Circadian homeostasis

Masri S, Papagiannakopoulos T, Kinouchi K, Liu Y, Cervantes M, Baldi P, Jacks T, Sassone-Corsi P. Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis. Cell. 2016 May 5;165(4):896-909. doi: 10.1016/j.cell.2016.04.039.

Assay Services Used:  Mouse Cytokine Array Discovery Assay, 32 Biomarker Multiplex
Disease/Biomarker Category: Developmental biology, Cancer

Dayton TL, Gocheva V, Miller KM, Israelsen WJ, Bhutkar A, Clish CB, Davidson SM, Luengo A, Bronson RT, Jacks T, Vander Heiden MG. Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma. Genes Dev. 2016 May 1;30(9):1020-33. doi: 10.1101/gad.278549.116.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Immunology, Inflammation

Arancibia S, Barrientos A, Torrejón J, Escobar A, Beltrán CJ. Copper oxide nanoparticles recruit macrophages and modulate nitric oxide, proinflammatory cytokines and PGE2 production through arginase activation. Nanomedicine (Lond). 2016 May;11(10):1237-51. doi: 10.2217/nnm.16.39.

Assay Services Used:  Mouse Cytokine Array
Disease/Biomarker Category: Immunology

Duerr CU, McCarthy CD, Mindt BC, Rubio M, Meli AP, Pothlichet J, Eva MM, Gauchat JF, Qureshi ST, Mazer BD, Mossman KL, Malo D, Gamero AM, Vidal SM, King IL, Sarfati M, Fritz JH. Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells. Nat Immunol. 2016 Jan;17(1):65-75. doi: 10.1038/ni.3308.

Assay Services Used:  Rat Cytokine Array Discovery Assay, 27 Biomarker Multiplex
Disease/Biomarker Category: Psychological stress, inflammation

Vecchiarelli HA, Gandhi CP, Gray JM, Morena M, Hassan KI, Hill MN. Divergent responses of inflammatory mediators within the amygdala and medial prefrontal cortex to acute psychological stress. Brain Behav Immun. 2016 Jan;51:70-91. doi: 10.1016/j.bbi.2015.07.026.