Description
Elevate your research with the TGFB 3-Plex Discovery Assay® Multi-Species Array, expertly designed for the advanced Luminex® 200™ platform.
This state-of-the-art multiplex assay enables the detailed analysis of three critical transforming growth factors—TGFβ1, TGFβ2, and TGFβ3—across multiple species. TGFβ signaling plays a pivotal role in numerous biological processes, including fibrosis, immune regulation, tissue regeneration, and cancer progression.
Key Features and Advantages
- Comprehensive Biomarker Detection: Analyze TGFβ1, TGFβ2, and TGFβ3 simultaneously to gain detailed insights into their individual and collective roles in various pathways.
- Multi-Species Compatibility: Suitable for Mouse, Human, Rat, Pig, Horse, Dog, and Cat species, this assay helps uncover insights into species-specific biological responses.
- Enhanced Pre-Analytical Processing: Our service includes acid extraction pre-treatment for all samples, enabling the release of the active form of TGFβ for optimal results. This meticulous process, performed by our expert team, is fully included in the assay cost.
- Advanced Multiplex Technology: Designed for the Luminex® platform, this assay ensures efficient detection of multiple biomarkers from a minimal single sample, maximizing precision and minimizing sample requirements.
Applications of the TGFB 3-Plex Discovery Assay®
- Fibrosis and Wound Healing:
- TGFβ1 is closely linked to fibrotic diseases and plays a key role in tissue repair and wound healing.
- Immune Regulation and Tissue Homeostasis:
- TGFβ2 is essential for development, maintaining tissue homeostasis, and modulating immune responses.
- Cancer Progression and Tissue Regeneration:
- TGFβ3 is vital in regulating immune suppression and tissue regeneration, making it a critical biomarker in cancer and regenerative medicine.
By analyzing these biomarkers together, researchers gain a comprehensive understanding of TGFβ activity, its role in biological pathways, and its implications in disease progression. This assay is ideal for studies in fibrosis, oncology, immune regulation, and regenerative biology.
Click here for information on shipping biological samples for Discovery Assays
Published Research Featuring Our TGFβ1-3:
- Nature! Klein, J., Wood, J., Jaycox, J. R., Dhodapkar, R. M., Lu, P., Gehlhausen, J. R., Tabachnikova, A., Greene, K., Tabacof, L., Malik, A. A., Silva Monteiro, V., Silva, J., Kamath, K., Zhang, M., Dhal, A., Ott, I. M., Valle, G., Peña-Hernández, M., Mao, T., Bhattacharjee, B., Takahashi, T., Lucas, C., Song, E., McCarthy, D., Breyman, E., Tosto-Mancuso, J., Dai, Y., Perotti, E., Akduman, K., Tzeng, T. J., Xu, L., Geraghty, A. C., Monje, M., Yildirim, I., Shon, J., Medzhitov, R., Lutchmansingh, D., Possick, J. D., Kaminski, N., Omer, S. B., Krumholz, H. M., Guan, L., Dela Cruz, C. S., van Dijk, D., Ring, A. M., Putrino, D., & Iwasaki, A. (2023). Distinguishing features of long COVID identified through immune profiling. Nature, 623(1), 139–148.
- Chen, K. S., Noureldein, M. H., McGinley, L. M., Hayes, J. M., Rigan, D. M., Kwentus, J. F., Mason, S. N., Mendelson, F. E., Savelieff, M. G., & Feldman, E. L. (2023). Human neural stem cells restore spatial memory in a transgenic Alzheimer’s disease mouse model by an immunomodulating mechanism. Frontiers in Aging Neuroscience, 15.
- Monroe, J. M., Quach, H. Q., Punia, S., Enninga, E. A. L., Fedyshyn, Y., Girsch, J. H., Fedyshyn, B., Lemens, M., Littlefield, D., Behl, S., Sintim-Aboagye, E., Mejia Plazas, M. C., Yamaoka, S., Ebihara, H., Pandey, A., Correia, C., Ung, C. Y., Li, H., Vassallo, R., Sun, J., Johnson, E. L., Olson, J. E., Theel, E. S., Badley, A. D., Kennedy, R. B., Theiler, R. N., & Chakraborty, R. (2024). Vertical transmission of SARS-CoV-2–specific antibodies and cytokine profiles in pregnancy. The Journal of Infectious Diseases, 229(2), 473–484.